VIBRANT-1.2.0
The QuickStart tutorial provides an introduction to basic DE functionality and navigation.
Please work through the tutorial and use the intercom button on the bottom right of this page if you have any questions.
Rationale and background:
VIBRANT is a tool for automated recovery and annotation of bacterial and archaeal viruses, determination of genome completeness, and characterization of virome function from metagenomic assemblies. VIBRANT uses neural networks of protein annotation signatures and genomic features to maximize the identification of highly diverse partial or complete viral genomes as well as excise integrated proviruses.
- Uses neural network machine learning of protein annotation signatures
- Assigns novel 'v-score' for determining the virus-like nature of all annotations
- Determines genome completeness
- Characterizes virome function by metabolic analysis
- Identifies auxiliary metabolic genes (AMGs)
- Excises integrated viral genomes from host scaffolds
- Performs well in diverse environments
- Recovers novel and abundant viral genomes
- Built for dsDNA, ssDNA and RNA viruses
VIBRANT uses three databases for identifying viruses and characterizing virome metabolic potential:
- KEGG (March release): https://www.genome.jp/kegg/ (FTP: ftp://ftp.genome.jp/pub/db/kofam/archives/2019-03-20/)
- Pfam (v32): https://pfam.xfam.org (FTP: ftp://ftp.ebi.ac.uk/pub/databases/Pfam/releases/Pfam32.0/)
- VOG (release 94):