2015 06 18 Genomics in Education Workshop - South Dakota State University/ University of South Dakota

2015 06 18 Genomics in Education Workshop - South Dakota State University/ University of South Dakota

Organizers:

S. Gibson, S. Subramanian, J. Williams

Local Point of Contact:

Susan Gibson

Trainers:

Uwe Hilgert, Jason WIlliams

Date:

June 18-19, 2015

Location:

South Dakota State University

Brookings, SD

Northern Plains Biostress Lab, SNP 67

Pre-Workshop Assignments

Confirm/Establish laptop compatibility:

Preparing your laptop:

  • Most laptops (<5 years old) updated with the latest web browser will have no problem. However, we do strongly recommend using the Firefox Browser (http://www.mozilla.org/en-US/firefox/fx/). Use of Internet Explorer will almost certainly cause problems, while Chrome has caused problems occasionally.Safari (Safari 4 or later) works well.

  •  Try to have administrative privileges on your computer (should it become necessary to install or update software during the workshop).

  •  Several workflows in the current version of DNA Subway require Java. Newer Java versions often limit some functionality in DNA Subway.

  • To test your Java installation, go to http://gfx.dnalc.org/files/apollo/test/ and follow the instructions at that site. The test is successful if a view of the Apollo annotation browser opens up that looks like this screenshot: //.

  • Should you experience difficulties, follow these steps:

    • Ensure that your computer is running the latest Java by going to http://java.com and click ‘Do I Have Java?’ Then click ‘Verify Java version.

    • If you are not running the latest Java, install or update it. (If you are a Mac user and experience trouble with this, contact williams@cshl.edu for additional advice).

    • Still having trouble opening Apollo? Open the Java settings (Control Panel or Systems Preferences), click Security tab. Add the following URLs to the Exception Site List:

    • If Java still does not open, enter into the Exception Site List as well. (One at a time.)

    • If none of the above worked, get Java 6 at this link:* http://java.com/en/download/manual_v6.jsp, and install it on your laptop.

Make sure you have a valid iPlant account:

Go through these readings and other assignments:

  • Review DNA Subway manual (a printed copy will be presented at the workshop)

  • Review DNA Barcoding laboratory (a printed copy will be presented at the workshop)

  • Bring a small sample of plant tissue (a leaf/flower/etc.) or collect one on campus before the experiment.

  • If you wish to bring sequence data for the DNA barcoding or genome annotation experiments feel free to do so! 

  • Check out the slides and papers listed/linked in the agenda below.

Workshop Agenda and Resources

Thursday

Room tba

WiFi:

Pwd:

Time

Topic

Slides

Notes/Links

08:30-9:00

Arrive / Set up Computers

 

 

09:00-09:15

Welcome/Logistics

 

 

09:15-09:45

Introductions

 

 

09:45-10:00

iPlant Collaborative & workshop objectives

iPlant Homepage
iPlant Account Portal

10:00-10:15

DNA Subway tour

 

DNA Subway Homepage

10:15-10:30

Break

 

 

10:30-12:00

Using the Red Line & DNA Annotation to Teach Concepts in Molecular Biology


Gene Annotation

GFX DNALC Server

12:00-01:00

Lunch

 

 

01:00-01:15

Mini Seminar: Evidence Based Gene Modeling

 

01:15-02:30

Annotate Genes I: On Your Own

 

ENCODE Project
ENCODE Nature

02:30-02:45

Break

 

 

02:45-03:00

Mini-Seminar: RNA Splicing

Alternative Splicing Paper

03:00-04:00

Annotate Genes II: User-BLAST

 

"User Evidence:" (save file to desktop, then upload to annotation project)
Additional EST data: http://gfx.dnalc.org/files/evidence/Annotation/

04:00-05:00

Demonstration: RNA-Seq and Green Line

 

 

 

 

 

Friday

Room tba

 

 

Time

Topic

Slides

Notes/Links

09:00-09:30

Review, Open Questions From Day 1

 

 

09:30-9:45

Mini Seminar: Transposons

 

09:45-10:30

Find Transposons in a Genome (Yellow Line)

 


Paper: TARGeT
Paper: Ping Transposon Burst in Rice Tissue Culture

Paper:

Slides:

10:30-10:45

Break

 

 

10:45-12:00

DNA Barcoding - Isolate DNA & Prep PCR

 

12:00-01:00

Lunch

 

 

01:00-01:15

Mini Seminar: DNA Barcoding and Student Projects

Urban Barcode Project

01:15-02:15

DNA Barcoding - Electrophorese and Prep DNA for Sequencing

 

 

02:15-02:30

Break

 

 

02:30-03:30

Analyze DNA Barcodes (Blue Line)

 

03:30-03:45

Evaluation, and Closure

 

Survey Link: https://www.surveymonkey.com/s/GenomicsInEducation_post

Other Websites and Links and Resources

Instructors

Name

Contact

Institution

Uwe Hilgert

hilgert at email.arizona.edu

iPlant Collaborative, BIO5 Institute, U of Arizona

Jason Williams

williams at cshl.edu

iPlant Collaborative, DNA Learning Center, Cold Spring Harbor Laboratory

Attendees

Name

Contact

Institution

DNA Barcoding Sample

Experimentor/Sample No.

No. on gel

Sequence IDs

Brian Blais

brian.blais at yellowjackets.bhsu.edu

Black Hills State U

Angiosperm at 44*18' 35.49' 96*45'40.35"

14

Gel #2 14

Experimentor14-F

Experimentor14-R

Elizabeth Bloomfield

bloomfieldl at divinechildhighschool.org

Divine Child HS

Tulip Tree

17

n/a

n/a

Heike Bücking

heike.bucking at sdstate.edu

South Dakota State U

Oxytropio lambertii

12

Gel #1 12

Experimentor12-F

Experimentor12-R

Catherine Chappell

cattchappell at gmail.com

Black Hills State U

Bass wood at 44*19' 14.65'"96*47'10.97"

13

Gel #2 13

Experimentor13-F

Experimentor13-R

Serge Danielson-Francois

sdanielso at ltu.edu

Divine Child HS

Small herbaceous something; same as SG

15

n/a

n/a

Anne Danielson-Francois

danfranc at umd.umich.edu

U Michigan - Dearborn

Blueberry

16

n/a

n/a

Carla Delucchi

cdelucchi at mccneb.edu

Metropolitan CC, Omaha, NE

Purple locoweed; Oxytropis lambertii

11

Gel #1 11

Experimentor11-F

Experimentor11-R

Gunbharpur Gill

Gunbharpur.Gill at yellowjackets.bhsu.edu

Black Hills State U

Purple loco weed

9

Gel #1 9

Experimentor09-F

Experimentor09-R

Anna Hafele

anna.hafele at yellowjackets.bhsu.edu

Black Hills State U

American bass wood at 44*19' 14.65'"96*47'10.97"

18

Gel #2 18

Experimentor18-F

Experimentor18-R

Ann Impullitti

impullit at augsburg.edu

Augsburg C

Soybean

6

Gel #1 6

Experimentor06-F

Experimentor06-R

Raeann Mettler

raeann.mettler at bhsu.edu

Black Hills State U

Some tree outside of Biostress Lab at SDSU

2

Gel #1 2

Experimento02-F

Experimentor02-R

Debra Mixon

debra.mixon at breckschool.org

Breck School

Daisy fleabane

21

Gel #2 21

Experimentor21-F

Experimentor21-R

Fangping Mu

fangping.mu at sdstate.edu

South Dakota State U

Green tree

10

Gel #1 10

Experimentor10-F

Experimentor10-R

Michael Oberle

michael.oberle at yellowjackets.bhsu.edu

Black Hills State U

Some weed at 44*19' 14.65'"

96*47'10.97"

7

Gel #1 7

Experimentor07-F

Experimentor07-R